Jesse Welles Nathan is a former actress. She provided voices for the animated films Wizards as Elinore and Hey Good Lookin' as Eva, directed by Ralph Bakshi. She played a lead role in three episodes of The Rockford Files: "Roundabout", "2 Into 5.56 Won't Go" and "A Different Drummer". She also appeared in season 4 of the sitcom Soap as a prostitute who gets romantically involved with Danny, and she was a regular on Husbands, Wives & Lovers.
She left acting and became an artist, and her work has been displayed at various galleries across Southern California, including the Schomburg Gallery. Her art style consists of mixed media with old photos drawn with balloons or vibrant colors.