San Francisco Police Commissioner Stewart "Mac" McMillan and his amateur detective wife keep their marriage unpredictable while solving the city's most baffling crimes.
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6 Seasons
Season 1
Season 17 Episodes
Season 2
Season 27 Episodes
Season 3
Season 36 Episodes
Season 4
Season 46 Episodes
Season 5
Season 57 Episodes
Season 6
Season 66 Episodes
Cast of McMillan and Wife
Rock HudsonStewart 'Mac' McMillan
John SchuckSgt. Charles Enright
Susan Saint JamesSally McMillan
Nancy WalkerMildred
Martha RayeAgetha
Richard GillilandSgt. Steve DiMaggio
Carole CookCarole Crenshaw
Jackie CooganHoward Sparks
John AstinSykes
Gloria StroockMaggie
Martin E. BrooksDeputy D.A. Chapman
James DobsonCherry Picker
Michael AnsaraMike Bolger
Paul Stewart
Pat Harrington, Jr.
Joshua Shelley
Lawrence PressmanPeter Jordan
John FiedlerSimpson
Richard DeaconLuther Dorfman
Dick HaymesFred Wesley
William DemarestCyrus McFee
Connie SawyerMrs. Goodbody
James KarenGeorge Pauling
Bill QuinnJudge Freeman
Kenneth MarsDr. Thursby
Lew PalterFlorist
Andrew DugganCaptain Robert Stiles
Liam DunnDave Duncan
Werner KlempererVan Doren
Barbara BossonDella Wheatley
Eve McVeaghMrs. Denny
Sharon AckerEvie Kendall
John Stephenson
Wally Cox
Karen Valentine
Barbara Barrie
Jeffrey Byron
Jennifer Leak
James Whitmore Jr.
Lloyd Bochner
Jason Wingreen
Lew Ayres
David Huddleston
Peter BreckGeorge Noland
Paul Winchell
Linda Evans
Ron Rifkin
Sheree North
Charlotte Rae
Peter Bonerz
Salome Jens
Murray Hamilton
Marj Dusay
Cameron Mitchell
John Vernon
Nina Foch
June Havoc
Dick Van Patten
Norman AldenRandy Baine
Vito Scotti
Cesare Danova
Slim Pickens
Paul Richards
Beverlee McKinsey
Albert Salmi
Susan Sullivan
Ron Silver
Tyne Daly
Carmen Zapata
Joe E. Ross
Scott Brady
Ed Flanders
Shepperd Strudwick
William Traylor
Lorraine Gary
Oscar Beregi Jr.
Van JohnsonHarry Jerome
JoAnna CameronVanessa Vale
Linda WatkinsEmily Hull
Samantha JonesLoretta
Barbara FeldonMargaret 'Maggie' Miller
James OlsonW.T. Knox
Tom BosleySam Hamilton
Edward AndrewsIsreal Black
Jessica WalterDonna Drake
Richard StahlDesk Clerk
Alejandro ReyMiguel Esteban
Nancy MaloneSandy Adams
Don BarrySam
Raymond SingerReporter
Gordon JumpDoctor (uncredited)
Murray MathesonAngus McFee
Robert DonnerPrice
Richard EasthamThomas Ewing
Stefanie PowersRachel Webley
William WindomTed Hoffenstein
George MaharisWalter Webley
Titos VandisMr. Boravitch
Kenneth TobeySgt. Halliday
Barry SullivanWalt Harmon
Donna MillsLaura Rainey
Larry PennellAgent Cushing
Don KeeferSelwyn
M. Emmet WalshOfficer Ames
Maudie PrickettMrs. Chandler
Rudy BondProprietor
David BirneyRandy Murphy / Randy Newmark III
Norman FellAllan Kovacs
Aneta CorsautHotel Desk Clerk (uncredited)
James HongJames Hong
R. G. ArmstrongSheriff Farraday
Pamela HensleyGwynneth Jerome
Scatman CrothersFloyd
Dick SargentDr. Jim Vale
Lola DeemNurse Fisher
Macdonald CareyDr. Gunther
Michael ConstantineDr. Eisner
Michael TolanDr. Alec Janetta
Eileen BrennanNora Dane
Arthur ToveyAudience Member (uncredited)
Andy RomanoPoliceman
Buddy HackettJoey Germaine
Rosey GrierBobo Johnson
Rhonda FlemingVera Royale
Dabney ColemanHansen
George SawayaAl
Tom PediNews Vendor
Ethelreda LeopoldClub Patron (uncredited)
William DanielsCommander Campbell
Stephen YoungLt. Don Corbett
Robert F. SimonMilitary Judge
Len LesserBenny Carr
David SoulJerry
Paul StevensBuddy Stone
Dennis PatrickLeon Silver
Bernie KopellBernini Mussolino
Walter BrookeD. A. Chapman
George GaynesBurton Rhoner
Peter BroccoTom Rhine, Sr.
Bob HarksPoliceman (uncredited)
Julie SommarsCarol Hanover
Jack JonesJohnny Barton
Marisa PavanHattie Carrara
Russell JohnsonCarl Jensen
Robert WebberCharles Meridio
Henry BeckmanHarry Court
Morgan JonesBrad
Allen WilliamsFlight Engineer
Keenan WynnProfessor Zagmeyer
Bobby TroupErrol Wilson
Marjorie BennettManager
Selma DiamondGas Station Attendant
Paul SorensenOfficer Ryan (uncredited)
Nehemiah PersoffClementa Habib
Donna DouglasRita
Gino ConfortiAldo
Ross HagenBrady
Barbara Baldavin1st Stewardess
Edmond O'BrienMr. Fontaine
Charles Nelson ReillyDavison
Nick DimitriCowboy Actor (uncredited)
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