Accompanied by guest correspondents at a round table, comedian Chelsea Handler discusses the latest in celebrity gossip and pop culture. She also interviews celebrities, but with a good dash of humor.
Where to Watch Season 4
197 Episodes
Robin Thicke
E1
Robin ThickeWe're starting off the new year with Robin Thicke and his Sex Therapy...like father like son. Comedian Jo Koy, comedian Christina Pazsitzky and comedian Guy Branum are on the panel.
Mary J. Blige
E2
Mary J. BligeWe're getting deep with Mary J. Blige and her new album, Stronger With Each Tear, word. Comedian Chris Hardwick, comedians Randy and Jason Sklar.
Holly Madison
E3
Holly MadisonWe're getting deep with Mary J. Blige and her new album, Stronger With Each Tear, word. Comedian Chris Hardwick, comedians Randy and Jason Sklar.
Joel David Moore
E4
Joel David MooreHolly Madison is dropping on by her old E! family today...we've missed her, too. Comedian Donnel Rawlings, comedian Heather McDonald and comedian Gary Valentine.
Giuliana & Bill Rancic
E5
Giuliana & Bill RancicWord on the street is Giuliana and Bill Rancic are trying to have a baby. What're the odds that we'll get any sort of big announcement? Comedian Brad Wollack, comedian Natasha Leggero and comedian Matt Braunger.
Aisha Tyler
E6
Aisha TylerWe welcome back the very funny Aisha Tyler, from the new show Archer. Comedian Jo Koy, comedian Loni Love and comedian Josh Wolf.
Amy Brenneman
E7
Amy BrennemanAmy Brenneman of Private Practice stops by, perhaps with some doctorly advice. Comedian John Caparulo, comedian Jen Kirkman and comedian Dan Levy.
Snooki, Pauly D and The Situation
E8
Snooki, Pauly D and The SituationFist pumps all around for Jersey Shore's Snooki, Pauly D and The Situation. Comedian Chris Franjola, comedian Whitney Cummings and TV personality Ross Mathews.
David Arquette
E9
David ArquetteDavid Arquette is back and telling us all about his new play The Female of the Species and the Golden Globes! Comedians Michelle Collins and Randy and Jason Sklar
Adrianne Palicki
E10
Adrianne PalickiClear eyes, full hearts, can't lose with Legion's Adrianne Palicki (aka FNL's Tyra). Comedian Chris Hardwick, actress-comedian Arden Myrin and comedian Eric Price.
Kaley Cuoco
E11
Kaley CuocoWho wouldn't be stoked that Kaley Cuoco from the megapopular Big Bang Theory is here? Comedian Heather McDonald, TV personality Ross Mathews and comedian Lavell Crawford.
James Van Der Beek
E12
James Van Der BeekJames Van Der Beek is in the new movie Formosa Betrayed and popping up all over TV—even here! E!'s own Michael Yo, comedian Sarah Colonna and comedian Guy Branum.
Katharine McPhee
E13
Katharine McPhee
Jill Scott
E14
Jill Scott
Dax Shepard
E15
Dax Shepard
Staff Book Club
E16
Staff Book Club
Camila Alves
E17
Camila Alves
Andy Whitfield
E18
Andy Whitfield
Shorty Rossi
E19
Shorty Rossi
Julie Benz
E20
Julie Benz
Ozzy Osbourne
E21
Ozzy Osbourne
Amanda Seyfried
E22
Amanda Seyfried
Dave Salmoni
E23
Dave SalmoniWe're beyond pleased to welcome back our animal guy Dave Salmoni and his new animal friends. Comedian Jo Koy, comedian Christina Pazsitzky and comedian Mo Mandel.
Channing Tatum
E24
Channing Tatum
Kate Flannery
E25
Kate FlanneryWe get down to business with The Office's Kate Flannery. Comedian Loni Love, comedian Dan Levy and comedian Whitney Cummings.
Jackie Collins
E26
Jackie CollinsThings get really scandalous when author Jackie Collins stops by with her new book, Poor Little Bitch Girl. Comedian Chris Hardwick, comedian Jen Kirkman and comedian Jo Koy.
Lisa Edelstein
E27
Lisa EdelsteinLisa Edelstein from House is back again...Wait, so who's running Princeton Plainsboro? Comedian Josh Wolf, comedian Heather McDonald and comedian Ryan Stout.
Eli Roth
E28
Eli Roth
Keshia Knight Pulliam
E29
Keshia Knight PulliamHouse of Payne's Keshia Knight Pulliam is one hard working lady; Dr. Huxtable would be so proud. Comedian Loni Love, TV personality Rove McManus and comedian Michelle Collins
Danica Patrick
E30
Danica PatrickWe're pretty thrilled that Danica Patrick makes a pit stop over at Chelsea Lately today. Comedian Josh Wolf, comedian Whitney Cummings and comedian Jo Koy.
Radha Mitchell
E31
Radha MitchellThings might get wild with Radha Mitchell star of the new thrilling horror movie The Crazies. Comedian John Caparulo, comedian Bill Bellamy and actress-comedian Arden Myrin.
Parker Posey
E32
Parker PoseyThe Chelsea Lately cast do a Kardashian skit. Comedian Brad Wollack, comedian Natasha Leggero and comedian Ben Gleib.
Sean William Scott
E33
Sean William ScottFrom the new movie Cop Out we've got Seann William Scott in our custody today. Comedian Chris Hardwick and Comedians Randy and Jason Sklar.
Kendra & Hank Baskett
E34
Kendra & Hank BaskettKendra and Hank Baskett are here to tell us all about the spellbinding new season of Kendra. E!'s own Michael Yo, comedian Sarah Colonna and comedian Jo Koy.
Single Staffers, Handler Edition
E35
Single Staffers, Handler EditionPlease enjoy a very special Handler Edition of Single Staffers. Comedian Matt Bruanger, comedian Heather McDonald and comedian Moshe Kasher.
Gabourey Sidibe
E36
Gabourey SidibeFrom Precious, the Academy Award-nominated Gabourey Sidibe is here. TV personality Ross Mathews, comedian Christina Pazsitzky and comedian Guy Branum.
Kevin McKidd
E37
Kevin McKiddSomeone got some time away from the O.R., Grey's Anatomy's Kevin McKidd is here. Comedian John Caparulo, comedian Arden Myrin and comedian Chris Franjola.
Chelsea Chelsea Bang Bang
E38
Chelsea Chelsea Bang BangChelsea Chelsea Bang Bang is in stores now...You're welcome, everyone. Comedian Brad Wollack, comedian Natasha Leggero and comedian Ben Gleib.
Amy Ryan
E39
Amy RyanChelsea Chelsea Bang Bang is in stores now...You're welcome, everyone. Comedian Brad Wollack, comedian Natasha Leggero and comedian Ben Gleib.
Pretty Wild Cast
E40
Pretty Wild CastAlexis Neiers, Gabrielle Neiers and Tess Taylor are here from their aptly titled new series on E! Pretty Wild. Comedian Brad Wollack, comedian Dan Levy and comedian Josh Wolf.
Shenae Grimes
E41
Shenae Grimes90210's Shenae Grimes is here to give us the deets on all things West Beverly. Comedian Bobby Lee, comedian T.J. Miller and comedian Whitney Cummings.
Rachael Harris
E42
Rachael HarrisFrom the highly anticipated Diary of a Wimpy Kid, the purely entertaining Rachael Harris is here. Comedian Jo Koy, comedian Loni Love and comedian Josh Wolf.
Avril Lavigne
E43
Avril LavigneWe catch up with Avril Lavigne, who sings "Alice," the title song from Tim Burton's Alice in Wonderland. Comedian Sarah Colonna, comedian/TV host Rove McManus and comedian Mo Mandel.
Duane "Dog" Chapman
E44
Duane "Dog" ChapmanWe're so thrilled to welcome the author of Where Mercy Is Shown, Mercy Is Given, Dog the Bounty Hunter. Comedian John Caparulo, comedian Heather McDonald and TV personality Ross Mathews.
Kelly Cutrone
E45
Kelly Cutrone
Scott Wolf
E46
Scott Wolf
Crispin Glover
E47
Crispin Glover
Blake Shelton
E48
Blake Shelton
Ludacris
E49
LudacrisLudacris is back with his new album Battle of the Sexes and this time he's bringing drinks. Comedian Ben Gleib, comedian Natasha Leggero and comedian Guy Branum.
Johnny Weir
E50
Johnny WeirJohnny Weir is here, and unfortunately our show is not "on ice" this week. Comedian Jo Koy, comedian Lil JJ and comedian Sarah Colonna.
Erykah Badu
E51
Erykah Badu
Justin Bieber
E52
Justin BieberChuy Bravo wrote a book, Little Nuggets of Wisdom, and he's here to share them. This, BTW, is all 100 percent for real, for real, girl. Comedian Heather McDonald, comedians Randy & Jason Sklar.
Jennifer Love Hewitt
E53
Jennifer Love HewittAuthor of The Day I Shot Cupid, Jennifer Love Hewitt is here. Comedian Brad Wollack, E!'s own Michael Yo and Comedian Mo Mandel,
Ed Asner
E54
Ed AsnerFind out how spunky Chelsea can really be when TV Icon and star of Up Ed Asner stops by. Comedian Josh Wolf, comedian Loni Love and comedian Wil Anderson.
Blake MyCoskie
E55
Blake MyCoskieThings get real philanthropic up in here with Tom's Shoes founder Blake Mycoskie. Comedian Greg Behrendt, comedian Jen Kirkman and comedian Matt Braunger.
Taraji P. Henson
E56
Taraji P. HensonFrom the highly anticipated movie Date Night, the Academy Award-nominated Taraji P. Henson is here. Comedian Chris Franjola, comedian Chris Hardwick, TV personality Ross Mathews.
Tiny & Toya
E57
Tiny & ToyaFrom BET's Tiny & Toya, BFFs Tiny & Toya are here. Comedian Whitney Cummings, actress Cloris Leachman and TV personality Ross Mathews.
Our 500th Episode
E58
Our 500th EpisodeCome celebrate a real milestone at Chelsea Lately—tonight's our 500th episode! Comedian Jo Koy, comedian Sarah Colonna and comedian Josh Wolf.
Dave Salmoni
E59
Dave SalmoniResident animal expert Dave Salmoni is back with some hopefully furry friends. Comedian Dan Levy, comedian Arden Myrin and comedian Lavell Crawford.
Erin Andrews & Maksim Chmerkovskiy
E60
Erin Andrews & Maksim ChmerkovskiyDancing With the Stars' hottest couple Erin Andrews and Maksim Chmerkovskiy. Comedian John Caparulo, comedian Heather McDonald and comedian Donnell Rawlings.
Gretchen Wilson
E61
Gretchen Wilson
Amy & Matt Roloff
E62
Amy & Matt Roloff
Katie Cassidy
E63
Katie Cassidy
Ted Allen
E64
Ted Allen
Michael Weatherly
E65
Michael Weatherly
Jerry Weintraub
E66
Jerry Weintraub
Jeffrey Dean Morgan
E67
Jeffrey Dean Morgan
Brooke Shields
E68
Brooke Shields
Molly Ringwald
E69
Molly Ringwald
Busy Philipps
E70
Busy Philipps
Monica
E71
Monica
Michael Lewis
E72
Michael Lewis
Amanda Seyfried
E73
Amanda Seyfried
Laura Bell Bundy
E74
Laura Bell Bundy
Asian Singles with Jo Koy
E75
Asian Singles with Jo Koy
Carson Kressley
E76
Carson Kressley
Bradley Whitford
E77
Bradley Whitford
Marisa Miller
E78
Marisa Miller
Mary Lynn Rajskub
E79
Mary Lynn Rajskub
Damon Wayans
E80
Damon Wayans
James Van Praagh
E81
James Van Praagh
Judge Lately
E82
Judge Lately
Tim Roth
E83
Tim Roth
Zach Gilford
E84
Zach Gilford
Snoop Dogg and Mike Epps
E85
Snoop Dogg and Mike Epps
Justin Halpern
E86
Justin HalpernThe man behind all things Shit My Dad Says, Justin Halpern is here. Comedian Bobby Lee, comedian Jen Kirkman and comedian Dov Davidoff.
Colin Hanks
E87
Colin HanksTonight we welcome Colin Hanks, one of The Good Guys from the new Fox drama. Comedian Heather McDonald, comedian Randy Sklar and musician Jeff Wild.
Clay Aiken
E88
Clay AikenClay Aiken is here, seriously, with his new CD Tried and True. Comedian Ben Gleib, comedian Loni Love and Comedian Gary Valentine.
Holly Madison
E89
Holly MadisonHolly Madison is back with her new show Holly's World. Comedian Chris Hardwick, comedian Guy Branum and actress-comedian Arden Myrin.
Stephen Moyer
E90
Stephen MoyerTrue Blood is returning and Stephen Moyer is here, so get excited...or scared?! I'm not really sure. Comedian Jo Koy, comedian Eric Price and comedian Chris Franjola.
Denis Leary
E91
Denis LearyStar of all things Rescue Me the hilarious Denis Leary is here. Comedian Steve Marmalstein, comedian Natasha Leggero and TV personality Ross Mathews.
Sarah McLachlan
E92
Sarah McLachlanWe're getting a little Lilith tonight when Sarah McLachlan stops by and talks her new album, Laws of Illusion. Comedian Jo Koy, E!'s own Michael Yo and comedian Sarah Colonna.
Lil Jon
E93
Lil JonWe're getting crunk with Lil Jon and his new album Crunk Rock…YEAAAAHHHH! Comedian John Caparulo, comedian Christina Pazsitzky and comedian Josh Wolf.
Roy Handler & Charley
E94
Roy Handler & CharleyLearn how to make cupcakes with Roy and Charley tonight. Comedian Brad Wollack, comedian Dan Levy and comedian Bobby Lee.
A.J. Khubani
E95
A.J. KhubaniLearn about the borderline amazing new As Seen on TV Products with A.J. Khubani. Comedian Chris Franjola, comedian Whitney Cummings and comedian Finesse Mitchell.
Mary McCormack
E96
Mary McCormackStar of In Plain Sight Mary McCormack graces us with her presence. Comedian Joe DeRosa, comedian Heather McDonald and comedian Josh Wolf.
Ron Artest
E97
Ron ArtestComedian Matt Braunger, comedian Moshe Kasher and comedian Guy Branum. Lakers champ Ron Artest tries to get into Chelsea's pants and chats about his NBA win. Plus, hear about his budding music career!
Ashley Greene
E98
Ashley GreeneActress Ashley Greene on her new movie, "The Twilight Saga: Eclipse"; Round table discussion with comics Mo Mandel, Arden Myrin, and Ross Mathews.
T.I.
E99
T.I.Rapper T.I. on his new album, "King Uncaged"; Round table discussion with comics Sarah Colonna, Jamie Kaler, and Josh Wolf.
Bryce Dallas Howard
E100
Bryce Dallas HowardFrom the most-anticipated movie in the country, Eclipse, Bryce Dallas Howard is here. Comedian Brad Wollack, comedian John Caparulo and comedian Christina Pazsitzky
Joe's Crab Shack
E101
Joe's Crab ShackCheck out Chuy as the new spokesperson for Joe's Crab Shack...You're welcome crabs. Comedian Bobby Lee, comedian Jo Koy and comedian Ben Gleib
Sam Trammell
E102
Sam TrammellTrue Blood's favorite shapeshifter Sam Trammell is back. Comedian Bobby Lee, comedian Jo Koy and comedian Ben Gleib
Claire Smith
E103
Claire SmithLearn about the summer's best drinks with Belvedere's Claire Smith. Comedian Jason Sklar, comedian Natasha Leggero and comedian Gary Valentine
Pharrell
E104
PharrellPharrell does a lot, like producing the soundtrack and composing the score for Despicable Me. Comedian Jo Koy, comedian Whitney Cummings and TV personality Ross Mathews.
Kristin Cavallari
E105
Kristin CavallariKristin Cavallari is here and has all the info you're dying to know about the final season of The Hills. Comedian Chris Hardwick, comedian Heather McDonald and comedian Dov Davidoff
Dave Salmoni
E106
Dave SalmoniCanadian animal trainer Dave Salmoni on his new show, "Savaged with Dave Salmoni"; Round table discussion with comics Jason Sklar, Natasha Leggero, and Gary Valentine.
Susan Sarandon
E107
Susan SarandonActress Susan Sarandon on her upcoming reality ping-pong series; Round table discussion with comics Jo Koy, Ben Gleib, and Brad Wollack.
Anna Paquin
E108
Anna PaquinSink your teeth into this: tonight we welcome Anna Paquin from HBO's True Blood. Rapper Lil John, rapper Big Boi and rapper Rick Ross.
Arsenio Hall
E109
Arsenio HallDust off your fists, girls, because Arsenio Hall is in the house. Comedian Chris Franjola, comedian Christina Pazsitzky and TV personality Ross Mathews
Frank Grillo
E110
Frank GrilloActor Frank Grillo on his show, "The Gates"; Round table discussion with comics Loni Love, Josh Wolf, and Greg Proops.
Kathy Griffin
E111
Kathy GriffinComedian Kathy Griffin on her show, "Kathy Griffin: My Life on the D-List"; Round table discussion with comics Jo Koy, Michael Yo, and Whitney Cummings.
Chicken Charlie
E112
Chicken CharlieFry cook Chicken Charlie discusses frying food; Round table discussion with comics Chris Hardwick, Heather McDonald, and Rove McManus.
Ron Livingston
E113
Ron LivingstonActor Ron Livingston on his new film, "Dinner with Schmucks"; Round table discussion with comics Ross Mathews, Sarah Colonna, Guy Branum.
Gabrielle Reece
E114
Gabrielle ReeceTonight's guest is volleyball pro Gabby Reece. At the Round Table: John Caparulo, Christina Pazsitzky, Matt Braunger.
Lisa Lampanelli
E115
Lisa LampanelliTonight's guest is actress Lisa Lampanelli. At the Round Table: Brad Wollack, Jo Koy, James Van Praagh.
Fat Joe
E116
Fat JoeFat Joe returns with his new album, The Darkside. Comedian Chris Franjola, actress-comedian Arden Myrin and TV personality Ross Mathews
Eva Mendes
E117
Eva MendesFrom The Other Guys, Eva Mendes is here. Comedian Dan Levy, comedian Natasha Leggero and comedian Ben Gleib.
Bethenny Frankel
E118
Bethenny FrankelStar of Bravo's Bethenny Getting Married?, Bethenny Frankel is here. Comedian Josh Wolf, comedian Whitney Cummings and comedian Guy Branum
Margaret Cho
E119
Margaret ChoMargaret Cho tells us about her new comedy/music album Cho Dependent. Comedian Heather McDonald, comedian Hyla Mathews and TV personality Ross Mathews.
Alanis Morissette
E120
Alanis MorissetteWe're checking in with Alanis Morissette who's working her acting chops on the new season of Weeds. Comedian Bobby Lee, comedian Loni Love and comedian Dov Davidoff.
Extra Round Table
E121
Extra Round TableExtra Round Table. Comedian Jo Koy, comedian Sarah Colonna and comedian Jason Sklar
Kim Raver
E122
Kim RaverGrey's Anatomy star Kim Raver tells us about her foray into the Lifetime TV movie, Bond of Silence. Comedian Finesse Mitchell, actress-comedian Arden Myrin, and TV personality Ross Mathews
Kim & Kourtney Kardashian
E123
Kim & Kourtney KardashianKim and Kourtney Kardashian are here to make sure everyone is still Keeping Up With the Kardashians. Comedian Bill Bellamy, comedian Natasha Leggero and comedian Josh Wolf.
Jennifer Aniston
E124
Jennifer AnistonJennifer Aniston is here telling us about her new film The Switch. Comedian John Caparulo, comedian Whitney Cummings and comedian Brad Wollack.
Elisabeth Shue
E125
Elisabeth ShueFrom the most frightening 3D movie of the summer, Piranha: 3D, Elisabeth Shue is here. Comedian Chris Franjola, comedian Owen Benjamin and comedian Jo Koy
Eli Roth
E126
Eli RothEli Roth tells us about his latest film The Last Exorcism. Comedian Chris Hardwick, comedian Sarah Colonna and comedian Gary Valentine.
Rufus Wainwright
E127
Rufus WainwrightRufus Wainwright tells us about his tour and latest CD, All Days are Nights: Songs for Lulu. Comedian Josh Wolf, comedian Heather McDonald and musician Jeff Wild.
Jerry Springer
E128
Jerry SpringerJerry Springer tells us about his foray into game shows as host of GSN's Baggage. Comedian Randy Sklar, comedian Christina Pazsitzky and comedian Guy Branum.
Angie Harmon
E129
Angie HarmonAngie Harmon tells us about her hugely popular show Rizzoli & Isles. Comedian Ben Gleib, comedian Godfrey and comedian Jo Koy
Jewel
E130
JewelJewel returns and tells us about her new album, Sweet and Wild. Comedian Brad Wollack, comedian Natasha Leggero and comedian Steve Marmalstein.
Louise Roe
E131
Louise RoeHost of CW's Plain Jane Louise Roe is here to make over the staff of Chelsea Lately. Comedian Josh Wolf, comedian John Caparulo and musician Jo Koy.
Extra Roundtable
E132
Extra RoundtableYou asked for more round table, tonight you're getting more round table. You're welcome, America. Comedian Chris Franjola, comedian Loni Love and comedian Joe DeRosa
Mel B
E133
Mel BMel B. tells us about her new Style Network show Mel B: It's a Scary Life. Comedian Greg Proops, actress-comedian Arden Myrin and comedian-host Rove McManus.
Ne-Yo
E134
Ne-YoR&B singer Ne-Yo on his new album, "Libra Scale "; Round table discussion with comics Michael Yo, Jen Kirkman, and Ross Mathews.
B.o.B.
E135
B.o.B.VMA performer and five-time nominee B.o.B is here with his No. 1 album B.o.B Presents: The Adventures of Bobby Ray. Comedian Matt Braunger, comedian Heather McDonald and comedian Josh Wolf.
Extra Roundtable
E136
Extra RoundtableAn extra-long Round Table. You're welcome, America. Comedian T. J. Miller, comedian Sarah Colonna and comedian Dov Davidoff.
Extra Roundtable
E137
Extra RoundtableAn extra-long Round Table. You're welcome, America. Comedian Ben Gleib, actress-comedian Whitney Cummings and comedian Jo Koy.
Emma Stone
E138
Emma StoneFrom Easy A, the can-do-no-wrong-in-my-book Emma Stone is here. Comedian Chris Hardwick, actress-comedian Arden Myrin and comedian Kevin Hart.
Snooki and Pauly D
E139
Snooki and Pauly DGet ready to GTL because Jersey Shore's Snooki and Pauly D are back. Comedian Donnell Rawlings, comedian Natasha Leggero and comedian Brad Wollack.
Usher
E140
UsherUsher has a new album, Versus, is on tour and is hanging out with us tonight, everyone rejoice. Comedian Loni Love, comedian Chris Franjola and musician Jeff Wild.
Jared Leto
E141
Jared LetoJared Leto, lead singer of the band '30 Seconds to Mars.' Comedian John Caparulo, comedian Guy Branum and comedian Lavell Crawford
Meghan McCain
E142
Meghan McCainWe welcome author of Dirty Sexy Politics, Meghan McCain. Comedian Josh Wolf, comedian Heather McDonald and comedian Gary Valentine.
Emily Rose
E143
Emily RoseEmily Rose from SyFy's Haven is here. Comedian Matt Braunger, comedian Sarah Colonna and comedian Mo Mandel.
Laird Hamilton
E144
Laird HamiltonWe're pretty stoked that world-renowned surfer Laird Hamilton returns tonight. Comedian Jason Sklar, comedian Michelle Collins and comedian Jo Koy.
Kristen Bell
E145
Kristen BellFrom the hilarious movie You Again, Jersey Shore's No. 1 fan Kristen Bell is here. Comedian Bobby Lee, comedian Whitney Cummings and TV personality Ross Mathews.
Adam Levine
E146
Adam LevineAdam Levine of Maroon 5 is here with their new album Hands All Over. Comedian Brad Wollack, comedian John Caparulo and writer Diablo Cody.
Taye Diggs
E147
Taye DiggsStar of Private Practice Taye Diggs is here…he may or may not be wearing a shirt. Comedian Jo Koy, comedian Dov Davidoff and comedian Natasha Leggero.
Dax Shepard
E148
Dax ShepardParenthood's Dax Shepard is here to discuss many a things, one being his new film The Freebie. Comedian Chris Franjola, comedian Dan Levy and TV personality Ross Mathews.
AnnaLynne McCord
E149
AnnaLynne McCordAnnaLynne McCord is here to give us the 411 on all things 90210. Comedian Chris Hardwick, comedian Ben Gleib and actress-comedian Arden Myrin.
Duane "Dog" Chapman, Beth Smith Chapman,
E150
Duane "Dog" Chapman, Beth Smith Chapman,Dog the Bounty Hunter's Beth and Duane "Dog" Chapman grace our stage tonight. Comedian Moshe Kasher, comedian Heather McDonald and comedian Josh Wolf.
Tommy Lee
E151
Tommy LeeTommy Lee is here with his latest Methods of Mayhem project A Public Disservice Announcement. TV personality Ross Mathews, comedian Whitney Cummings and comedian Guy Branum.
Kelly Osbourne
E152
Kelly OsbourneCohost of E!'s Fashion Police, Kelly Osbourne, is here. Comedian Jo Koy, comedian Randy Sklar and comedian Loni Love.
Trace Adkins
E153
Trace AdkinsThe cowboy himself, Trace Adkins, is back with his new album Cowboy's Back in Town. Comedian Brad Wollack, comedian Chris Hardwick and comedian Natasha Leggero.
Leah Remini
E154
Leah ReminiCohost of the new CBS talk show The Talk, Leah Remini is here. Comedian Jo Koy, comedian Sarah Colonna and comedian Greg Proops.
Lauren Conrad
E155
Lauren ConradAuthor of Sugar and Spice and Lauren Conrad Style the very busy Lauren Conrad is here. Comedian John Caparulo, comedian Josh Wolf and comedian Jim Breuer.
Amy Brenneman
E156
Amy BrennemanFrom Private Practice, the delightful Amy Brenneman returns to the show tonight. Comedian Chris Franjola, actress-comedian Arden Myrin and comedian Kevin Hart.
Johnny Knoxville
E157
Johnny KnoxvilleThe biggest jackass of them all, Johnny Knoxville from Jackass 3D is here. Comedian Ben Gleib, comedian Loni Love and TV personality Ross Mathews.
Blake Shelton
E158
Blake SheltonThe newest member of the Grand Ole Opry, Blake Shelton is here with his new album All About Tonight. Comedian Jo Koy, comedian Heather McDonald and E!'s own Michael Yo.
Lloyd Banks
E159
Lloyd BanksRapper Lloyd Banks. Comedian John Caparulo, comedian Whitney Cummings and comedian Donnell Rawlings.
Jenny McCarthy
E160
Jenny McCarthyJenny McCarthy is back with her latest book Love, Lust, and Faking It. Comedian Josh Wolf, musician Jeff Wild and comedian Guy Branum.
Julian McMahon
E161
Julian McMahonFrom the film Red Julian McMahon graces us with his presence tonight. Comedian Jo Koy, actress-comedian Arden Myrin, and TV personality Ross Mathews.
Milla Jovovich
E162
Milla JovovichMilla Jovovich returns to tell us about her new film Stone. Comedian Josh Wolf, comedian Chris Franjola and comedian Gary Valentine.
Jennifer Nettles
E163
Jennifer NettlesJennifer Nettles of Sugarland returns tonight with their new album The Incredible Machine. Comedian John Caparulo, comedian Sarah Colonna and comedian Chris Hardwick.
Nick Swardson
E164
Nick SwardsonFrom Nick Swardson's Pretend Time comedian Nick Swardson is here. Comedian Brad Wollack, comedian Michelle Collins and comedian Bobby Lee.
Eddie Izzard
E165
Eddie IzzardEddie Izzard from Showtime's United States of Tara is here. Comedian Jo Koy, comedian Natasha Leggero and comedian Ryan Stout.
Benji & Joel Madden
E166
Benji & Joel MaddenBenji and Joel Madden are here to tell us all about Good Charlotte's new album Cardiology. Comedian Josh Wolf, comedian Heather McDonald and comedian Bill Bellamy.
Emily Procter
E167
Emily ProcterProbably the most pregnant cast member of CSI: Miami, Emily Procter is here. Comedian Dan Levy, comedian Chris Franjola and comedian Sarah Colonna.
Connie Britton
E168
Connie BrittonFrom dare I say the greatest television show of all time (Friday Night Lights), we welcome Tami Taylor herself, the Emmy-nominated Connie Britton. Writer Diablo Cody, comedian Guy Branum and TV personality Ross Mathews.
Keenan Cahill
E169
Keenan CahillWe've got YouTube sensation Keenan Cahill debuting his brand new video on the show tonight. Comedian Josh Wolf, comedian Chris Franjola and comedian Sarah Colonna
Kendra Wilkinson-Baskett
E170
Kendra Wilkinson-BaskettKendra Wilkinson-Baskett is here to tell us all about the new season of her show Kendra. Comedian Jo Koy, comedian Matt Braunger and comedian Chris Hardwick
Starsky & Cox
E171
Starsky & CoxFind out how all of the stars align tonight with cosmic astrologists Starsky and Cox. Comedian Loni Love, comedian John Caparulo and TV personality Ross Mathews
Florence Welch
E172
Florence WelchFlorence Welch, from one of this year's hottest acts, Florence + the Machine, is here. Comedian Jim Norton, comedian Brad Wollack and actress-comedian Arden Myrin
Monica Potter
E173
Monica PotterFrom one of the best shows on TV, Parenthood, Monica Potter is here. Comedian Josh Wolf, comedian Natasha Leggero and comedian Greg Proops
Trey Songz
E174
Trey SongzTrey Songz is bringing his Passion Pain and Pleasure (also the name of his new CD) to the show tonight, word. Comedian Jo Koy, comedian Heather McDonald and comedian T.J. Miller
Tom Bergeron
E175
Tom BergeronDancing With the Stars' extraordinary host and Deb's BFF (sorry, Gary) Tom Bergeron is here. Comedian Dan Levy, comedian Sarah Colonna and comedian Gary Valentine
Nelly
E176
NellyNelly is dropping by with his new album 5.0. This is for real, this is not just a dream...nailed it. Comedian Chris Franjola, E! News correspondent Michael Yo and TV personality Ross Mathews
Single security guards
E177
Single security guardsIt's the return of Single Staffers...just in time for the holiday season, you're welcome America! Comedian John Caparulo, actress-Comedian Arden Myrin and comedian Ryan Stout.
Dane Cook
E178
Dane CookDane Cook is here with his greatest hits album, I Did My Best. Comedian Jo Koy, comedian Kevin Hart and comedian Ben Gleib
Taylor Swift
E179
Taylor SwiftTaylor Swift has a new album, called Speak Now, and she's here to tell us all about it. Topless comedian Brad Wollack, comedian Loni Love and comedian Gary Valentine
Donald Schultz
E180
Donald SchultzAnimal expert Donald Schultz is here with an alligator, a prairie dog and a rattlesnake. Comedian Bobby Lee, comedian Whitney Cummings and TV personality Ross Mathews
John Stamos
E181
John StamosOne of the greatest gifts television has ever given us, John Stamos who's been guesting on Glee is here. Comedian Josh Wolf, comedian Heather McDonald and TV personality Ross Mathews
Flo Rida
E182
Flo RidaFlo Rida is here with his new album Only 1 Flo and hopefully some explanation for the state of Florida. Comedian Jo Koy, comedian Sarah Colonna and comedian Mo Mandel
Cee-Lo Green
E183
Cee-Lo GreenTonight we welcome The Lady Killer himself Cee-Lo Green. Topless Comedian Chris Hardwick, comedian Natasha Leggero and comedian Chris Franjola
Kate Bosworth
E184
Kate BosworthFrom the new film The Warrior's Way Kate Bosworth is here. Comedian John Caparulo, comedian Matt Braunger and writer Diablo Cody
Tom Arnold
E185
Tom Arnold
Lucy Liu
E186
Lucy Liu
Keri Hilson
E187
Keri Hilson
Kathy Griffi
E188
Kathy Griffi
Nicki Minaj
E189
Nicki Minaj
Cat Cora
E190
Cat Cora
Ciara
E191
Ciara
Amy Adams
E192
Amy Adams
Diddy-Dirty Money
E193
Diddy-Dirty Money
Reese Witherspoon
E194
Reese Witherspoon
Crystal Bowersox
E195
Crystal Bowersox
Natasha Bedingfield
E196
Natasha Bedingfield
Keyshia Cole
E197
Keyshia Cole
Cast of Season 4
Chelsea HandlerHerself - Host
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