South Park: The End of Obesity

South Park: The End of Obesity
Weight loss drugs are all the rage though obtaining them can be problematic. However, some of the mothers of South Park clearly have no problem in obtaining them, as Randy Marsh discovers. Meanwhile, Cartman is desperately wanting to lose weight and a weight loss drug would be ideal for him.
Manuel Frangis reviewedMarch 9, 2025
I just watched South Park: The End of Obesity, and it’s easily a 5 out of 5 stars for me. This special is South Park at its best, brutal, hilarious, and perfectly timed with real-world issues. They take on the craze around Ozempic and weight-loss drugs in the way only South Park can, mixing social commentary with absolute absurdity.
The story kicks off with Cartman trying to get his hands on Ozempic after realizing how effective it is, only to find out that it’s way too expensive for him. This leads to a classic Cartman scheme with him and the boys trying to get access to the drug while taking shots at the healthcare system and pharmaceutical industry. Meanwhile, Randy gets caught up in his own mess when he realizes all the moms in town are suddenly getting slim on semaglutide and decides he wants in. It’s got that perfect mix of personal stupidity and larger satire that South Park does so well.
One of the best parts of the episode is the introduction of the cereal mascots as a literal mafia, furious that weight-loss drugs are ruining their sugary empire. It’s such a ridiculous idea but also so spot-on, making fun of how the food industry has played a huge role in obesity while pretending they aren’t responsible. Seeing these cartoon mascots acting like mob bosses is easily one of the funniest things South Park has done in years.
They also go after celebrity culture in the best way, especially with the running joke that listening to Lizzo’s music can replace Ozempic. It’s so dumb but so funny, especially since even Lizzo herself ended up embracing the joke.
The pacing is perfect, the jokes land hard, and there’s just enough truth in the satire to make it sting. It’s exactly what South Park should be, taking a real issue, pushing it to the absolute extreme, and making you laugh while also realizing how ridiculous reality actually is.
Final thoughts This is South Park doing what South Park does best. It’s sharp, funny, and completely unfiltered in its takedown of the weight-loss craze. If you love South Park, this is an instant classic.