Filmography
| 2021 | Girls5eva · as T.k. |
| 2020 | Central Park · as Shauna (voice) |
| 2019 | You're Not a Monster · as Mermaid / Gremlin |
| 2019 | Tuca & Bertie · as Dakota |
| 2017 | Big Mouth · as Auntie Amber |
| 2017 | Detroiters · as Molly |
| 2014 | Last Week Tonight with John Oliver · as Mom |
| 2014 | Wish It Inc. · as Shari |
| 2012 | Animation Domination High-Def · as Misty |
| 2012 | Above Average Presents · as Nurse |
| 2012 | Key & Peele · as Party Wife |
| 2025 | It's Dorothy! · as Self |
| 2024 | |
| 2024 | Have I Got News for You (US) · as Self - Team Captain |
| 2023 | Black Pop · as Self - Host, 'the Amber Ruffin Show' |
| 2022 | 2022: Back That Year Up · as Self |
| 2022 | The Wheel (US) · as Self - Expert |
| 2022 | The Jennifer Hudson Show · as Self - Guest |
| 2022 | Sherri (2022) · as Self |
| 2022 | Gutsy · as Self |
| 2022 | |
| 2022 | Would I Lie to You? (US) · as Self - Guest |
| 2021 | The Story of Late Night · as SelfPå Plex |
| 2021 | Doing the Most with Phoebe Robinson · as Self |
| 2020 | The Amber Ruffin Show · as Self - Host |
| 2020 | Wilmore · as Self |
| 2020 | Celebrity Game Face · as Self - Contestant |
| 2020 | GMA3: What You Need to Know · as Self |
| 2020 | |
| 2020 | |
| 2019 | A Little Late with Lilly Singh · as Self - Guest |
| 2019 | The Kelly Clarkson Show · as Self - Guest |
| 2019 | Tamron Hall · as Self - Guest |
| 2018 | The Shop: Uninterrupted · as Self |
| 2018 | The Break with Michelle Wolf · as Self - Special Guest |
| 2018 | Miley's New Year's Eve Party · as Self - Host |
| 2017 | Carpool Karaoke · as Self |
| 2016 | Full Frontal with Samantha Bee · as Self |
| 2015 | The Late Show with Stephen Colbert · as Self - Guest |
| 2014 | Late Night with Seth Meyers · as Self |
| 2013 | The Real Daytime · as Self |
| 2013 | Drunk History · as Herself - Narrator |
| 2010 | Family Feud · as Self - Contestant |
| 2009 | Watch What Happens Live with Andy Cohen · as Self - Guest |
| 2008 | Celebrity Family Feud · as Self - Contestant |
| 2008 | The Wendy Williams Show · as Self |
| 2007 | Morning Joe · as Self |
| 2003 | The Ellen DeGeneres Show · as Self - Guest |
| 1997 | The View · as Self - Guest Co-Host |
| 1979 | CBS Sunday Morning With Jane Pauley · as Self - Guest |
| 1975 | PBS News · as Self - Staff Writer: Late Night With Seth Meyer |
| 1952 | Today · as Self - Guest |
| 2020 | The Amber Ruffin Show · as Executive Producer |
| 2022 | The 75th Annual Tony Awards · as Special Material By |
| 2020 | |
| 2019 | 2019 Golden Globe Awards · as Special Material By |
| 2018 | 75th Golden Globe Awards · as Special Material By |
| 2017 | Detroiters · as Written By |
| 2014 | The 66th Primetime Emmy Awards · as Written By |
| 2014 | Late Night with Seth Meyers · as Written By |