When attractive Staff Nurse Sandra Nicholl joins the Holby she has problems dealing with an HIV-positive patient, whilst Julian and Jimmy find themselves attractive to her. A reluctant bridegroom involved in a car accident has his fiancée looks to his best friend for an explanation and an anorexic dancer's rushed to the hospital. Julian has to perform an emergency operation and a little boy's rushed in unconscious and the team battle to save him. Lisa Duffin and Paul argue and split up.
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Cast of The Last Word