Tom KennyDog / Cliff (voice) Carlos AlazraquiWinslow / Lube (voice) Maria BamfordShriek (voice) Billy WestRancid Rabbit (voice) John KassirDunglap / Mervis (voice) Nika FuttermanLola (voice) Dwight SchultzEddie the Squirrel (voice) Laraine NewmanIngrid Twins (voice) Peter HannanBalloon Guy (voice) / Theme Song Performance / Story Dave ThomasMean Bob (voice) Rob PaulsenStanky (voice) April WinchellSpace Grannies (voice) Dee Dee GreeneGreaser Baby Girl (voice) Brian Doyle-MurraySanta Claus Greg BursonBarry the Baboon (voice) Rodger BumpassPig / Man (voice) Jane KrakowskiCatDog's Mother (voice) Billy Bob ThorntonCatDog's Father (voice) Julianne BuescherCatrina (voice) Andrea MartinTalluhla / Indian (voice) Gail MatthiusFeline (voice) Tom KaneEvil Eric (voice) Kath SoucieLorraine (voice) Edie McClurgMrs. Grock (voice) Peter MacNicolRunt (voice) Teresa ParenteMaria Cowess / Mrs. Banks (voice) Cole HannanCat Fanatic (voice) Ruby HannanCat Fanatic (voice) Robert PorterRegisseur / Schrijver Derek DrymonRegisseur / Schrijver Marlene Robinson MayRegisseur Gary McCarverRegisseur / Animation Director Larry LeichliterRegisseur Robert LamoreauxSchrijver Barry StringfellowSchrijver Frank SantopadreSchrijver Antoine GuilbaudSchrijver Julia Jane LewaldSchrijver Peter HannanBalloon Guy (voice) / Theme Song Performance / Story 
