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Osmosis Jones
Directed by
Bobby Farrelly
,
Peter Farrelly
PG
2001
1h 35m
Comedy
,
Action
,
and more
6.3
55%
42%
Add to Watchlist
A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.
More
Where to Watch Osmosis Jones
Fandango at Home Free
Free
Hoopla
Free
Tubi TV
Free
+5 more
Cast of Osmosis Jones
Chris Rock
Osmosis Jones (voice)
Laurence Fishburne
Thrax (voice)
David Hyde Pierce
Drix (voice)
Brandy Norwood
Leah (voice)
Bill Murray
Frank Detorre
Molly Shannon
Mrs. Boyd
William Shatner
Mayor Phlegmming (voice)
Ron Howard
Tom Colonic (voice)
Sherry Lynn
(voice)
Mickie McGowan
Additional Character Voice (voice)
Chris Elliott
Bob
Elena Franklin
Shane Detorre
Kid Rock
Kidney Rock
Uncle Kracker
Kidney Rock (voice)
Carlos Alazraqui
Additional Character Voices (voice)
Rodger Bumpass
Additional Character Voices (voice)
Richard Steven Horvitz
Additional Character Voices (voice)
Danny Mann
Additional Character Voices (voice)
Jonathan Adams
Additional Character Voices (voice)
Bobby Farrelly
Director / Producer
Peter Farrelly
Director / Producer
Marc Hyman
Writer
Bob Camp
Writer
Steve Fonti
Writer
Mark Andrews
Writer
Barry Caldwell
Writer
Zak Penn
Producer
Bradley Thomas
Producer
Dennis Edwards
Producer
Osmosis Jones Ratings & Reviews
Lincoln and Blake Frank
June 13, 2025
A great cartoon and learn something new
Common Sense Media
Nell Minow
Mostly animated PG film has gross-out humor, violence.
Austin Chronicle
Kimberley Jones
The ideas are there, hints of genius, but no one ignites them.
Salon.com
Bill Wyman
Remains stubbornly one-dimensional.
eye WEEKLY
Adam Nayman
Folks who go to it expecting the traditional Farrelly flood of bodily fluids won't be disappointed, but it's likely they'll laugh harder at the witty dialogue and references to other films.
Washington Post
Rita Kempley
It should have been placed in a hazardous waste container, encased in concrete and dumped into the Farrelly brothers' septic tank.
Seattle Times
Mark Rahner
A very clever, very gross, very funny spoof of the clichd cop genre.
San Francisco Chronicle
Wesley Morris
Isn't a movie so much as a health-class nutrition lecture.
Orlando Sentinel
Jay Boyar
A hilarious, hellzapoppin' hybrid.
New York Post
Jonathan Foreman
It's no funnier than your average grade-school biology lesson and less pedagogically useful than your typical Farrelly brothers comedy.
Detroit News
Susan Stark
In more parts than not, Osmosis Jones is funny as it is fearless.
Denver Post
Steven Rosen
I really enjoyed Kroon and Sito's movie, but disliked the Farrellys. It's time they try harder - their style has grown sickening. And it's time Kroon and Sito make both halves of a film.
Boston Globe
Jay Carr
It's lively enough and passably entertaining, even if you may need a barf bag to get through it.
New York Times
Elvis Mitchell
Osmosis Jones, with its effluvia-festival brand of humor, is often fun, and the rounded, blobby rendering of the characters is likable.
Chicago Sun-Times
Roger Ebert
Likely to entertain kids, who seem to like jokes about anatomical plumbing. For adults, there is the exuberance of the animation and the energy of the whole movie, which is just plain clever.
Houston Chronicle
Eric Harrison
Movies are easier to enjoy when you aren't always covering your eyes.
Detroit Free Press
Terry Lawson
Though juvenile tastelessness continues to run rampant, Osmosis Jones can at least be safely enjoyed by most juveniles, who will also get a valuable lesson in what a lifetime of junk-food abuse can do.
USA Today
Claudia Puig
Adults might remain immune to the process of Osmosis, but younger viewers probably will be receptive to its nervy fun.
Rolling Stone
Peter Travers
Too crude for the kids and not crude enough for connoisseurs of the Something About Mary school of hair jism and balls caught in zippers, Osmosis Jones seems doomed to fall between the cracks.
Philadelphia Inquirer
Carrie Rickey
Has more ambition and imagination than can be comfortably contained in its brief 83 minutes.
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