

Osmosis Jones
Directed by Peter Farrelly, Bobby FarrellyA policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying Frank, the person they live in.
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Osmosis Jones Ratings & Reviews
- Lincoln and Blake FrankJune 13, 2025A great cartoon and learn something new
- mickerdooApril 13, 2026Gross. But actually pretty original and creative. Chris Rock makes for a fun lead. Animation feels similar to Space Jam.
- christinav61November 19, 2025I love this movie! it’s entertaining. It’s a good movie. People might not like this movie, but I like it.
- NonFebruary 15, 2026Western Cells at Work that's radical with a skateboard! Just a little dated/simplified on the bioscience aspects
- RichardDecember 19, 2025First saw this one on TV back in the day and honestly, that’s still the ideal format for it, the kind of movie you stumble onto while channel surfing and think, “Sure, why not.” The animated inside the body stuff is fun enough, but the live action segments feel like they escaped from a different (and much stickier) movie entirely. It’s quirky, chaotic and occasionally clever, but it never fully gels into something great. Streamed it now, and it was… okay. A nostalgic curiosity more than a must watch, but it does scratch that early 2000s weird energy itch.
- johnmartinryanDecember 9, 2025A fun kids movie that I grew up watching! Great jokes in there for the adults as well. The fact that they have so many comedians in the cast is a huge bonus! And the animation style is unique collaborating it with real footage.
Osmosis Jones Trivia
Osmosis Jones was released on August 10, 2001.
Osmosis Jones was directed by Peter Farrelly, Bobby Farrelly.
Osmosis Jones has a runtime of 1h 35m.
Osmosis Jones was produced by Zak Penn, Bradley Thomas, Peter Farrelly, Bobby Farrelly, Dennis Edwards.
A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying Frank, the person they live in.
The key characters in Osmosis Jones are Osmosis Jones (voice) (Chris Rock), Thrax (voice) (Laurence Fishburne), Drix (voice) (David Hyde Pierce).
Osmosis Jones is rated PG.
Osmosis Jones is a Comedy, Action, Adventure film.
Osmosis Jones has an audience rating of 4.2 out of 10.
Osmosis Jones had a budget of $75M.
Osmosis Jones has made $13.6M at the box office.






















