Jean SmartPickles Oblong (voice) Will FerrellBob Oblong (voice) Pamela AdlonMilo Oblong / Jared Klimer / The Debbies (voice) Lea DeLariaHelga Phugly (voice) Jeannie EliasBeth Oblong / Creepy Susie / Mikey Butts (voice) Randy SklarBiff Oblong (voice) Jason SklarChip Oblong (voice) Billy WestGeorge Klimer (voice) Becky ThyreJawless Peggy Weggy / Pristine Klimer / Debbie Klimer (voice) Laraine NewmanAdditional Voices (voice) Maurice LaMarcheAdditional Voices (voice) Jim CummingsSewer Workers (voice) Debra WilsonPrincipal Davis (voice) Carrie AizleyAdditional Voices (voice) Mark HamillMr. Phugly (voice) Susan KrebsMrs. Phugly (voice) Dan GreenCEO Guard (voice) Phil LaMarrAdditional Voices (voice) Michelle RuffYvette (voice) Charlie AdlerExecutive #1 (voice) Gary McCarverRegista / Storyboard Joey SolowaySceneggiatore Leonard DickSceneggiatore Eric FriedmanSceneggiatore Jace RichdaleSceneggiatore John LinnellTheme Song Performance John FlansburghTheme Song Performance Danny WeinkaufTheme Song Performance Marty BellerTheme Song Performance Dan MillerTheme Song Performance Richard J. GasparianAnimation Manager 
