Three twenty-something best friends living in Los Angeles are having the best--and worst--times of their lives, but through it all, they know that no matter what, they will always have one another's friendship.
Where to Watch Significant Others (1998)
1 Season
(1998) season 1
(1998) season 16 Episodes
Cast of Significant Others (1998)
Michael WeatherlyBen Chasen
Eion Bailey
Scott Bairstow
Elizabeth MitchellJane Chasen
Jennifer GarnerNell
Gigi Rice
Richard Masur
Nicki Aycox
Channon Roe
Joseph D. Reitman
Shirley Knight
Robert Desiderio
Victor Raider-Wexler
John Billingsley
Dan Bucatinsky
Michael Spiller
Carrie Preston
Ali Landry
Daniel von Bargen
Lawrence Pressman
Marisol Padilla Sánchez
Jack Knight
Kenneth Kimmins
Drew Tyler Bell
Fred Ornstein
Sonia Iris Lozada
Scott WinantDirector
Michael EnglerDirector
Christopher KeyserWriter / Producer
Amy LippmanWriter
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